Based on Permenkes RI No. 86 of 2013 the need for orthopedic implants in the jaw / face is increasing. In orthopedics, implants are devices that are placed in place of bone to support fractures. Referring to the statement, Balai Besar Logam dan Mesin (BBLM) conducted research on the manufacture of orthopedic implant products for the face using Metal Injection Molding (MIM) technology. MIM is a combination of the characteristics of Powder Metallurgy and Plastic Injection Molding for the production of complex metal components. The injection process is a major factor that needs to be considered to prevent injection defects including incomplete fill defects in order to proceed to the post-molding process. Based on this, it is necessary to simulate and analyze process parameters to find the maximum process parameters in order to prevent incomplete fill defects. The analysis was carried out using injection molding simulation software, namely Sigmasoft, to the previously obtained design, with a variation setting of the filling temperature value of 170°C-190°C and filling time of 0.5s-2.5s. Variations in values are processed to obtain a combination of parameter settings analyzed. The simulation software generates filling pressure values and filling percentages in the mold cavity. Demonstrate optimal parameters for green part orthopedic implants with Catamold 316L feedstock. The optimal injection operating parameters are at a melting temperature of 180°C, filling time of 1s and filling pressure of 700 bar.