ABSTRACT:Recent few decades many ontology have been developed for various domains which mostly includes educational domain, agricultural domain and biomedical domain. Particularly in the biomedical domain, large set of ontologies were developed to integrate variety of genomic information. Gene related functional information is stored in various databases after the sequencing of human genome in 2003. Searching of the information for any purpose it becomes essential to understand the schema of database to fetch information, which has becomes the time consuming and complex task. . This paper provides a unified framework that integrate diverse source of genomic data from various repositories such as ontologies and data bases using ontology based approach. The proposed ontology design coverst all possible relations for genomic data such as gene names and its products, gene types, gene identifier, mapping indexes in various repositories for genes, etc. The proposed ontology design is presented in terms of ontological concepts and the ontology design is evaluated in terms of syntax, structure and semantics using various evaluation metrics. The experimental result of our ontology shows that the proposed ontology is designed with well defined classes and conceptual relationships.