Total Knee Replacement (TKR) is a treatment of knee osteoarthritis to alleviate pain symptoms and improve physical functioning when other conservative treatments have failed. However, some patients still complaining of persistent post surgical pain (PPSP) after TKR. Although the cause of PPSP is not known, it seems that some of the patients with PPSP after TKR suffer from neuropathic pain. Recently genicular nerve radio-frequency ablation has emerged as an alternative intervention for patients at high risk who are unable to undergo surgical intervention. We have shown from our case, a 69-year old lady who had right total knee replacement presented with neuropathic knee pain has good symptom relieves after undergone radio-frequency ablation.

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