BMI, not BF or waist, is consistently and independently related to BP levels in children; overweight and obesity considerably increase the risk of hypertension.
Aims The aim of this study was to ascertain the prevalence of high and low WBC count on admission among the cases of probable and culture proven neonatal sepsis, and its affect on mortality rate. Methods WBC count (by Madonic CA 620 analyzer) of all patients admitted in NICU, Fazl-e-Omar Hospital, Rabwah with provisional diagnosis of neonatal sepsis were recorded. Cases of culture proven sepsis, or probable sepsis were included in this study and were treated with appropriate antibiotics. Background and Aims Early onset sepsis is a serious condition, with challenging diagnosis.C-Reactive Protein cut-off values for treatment vary according to different authors and protocols from 5 mg/L to 50 mg/L.The objective of this study was to determine the CRP cut-off value in septic screening of term and near term NB. Methods All NB with gestational age (GA) ³ 35 weeks admitted to the nursery of a tertiary hospital in the course of one year, with risk for early neonatal sepsis where included.We collected data from all analysis (CRP/CBC) until treatment decision, peripheral blood-culture and clinical findings.A positive septic screening (indicating treatment) resulted from a score involving CRP and leukocy te/neutrophil count.Newborns were thereafter included in the category "presumption of infection" (POI) if they met at least one of the following criteria: CRP > 50 mg/L; maternal sepsis; NB with positive bloodculture; several positive markers and subtle clinical features; multiple risk factors and subtle clinical features. Results From 2478 NB admitted, 193 were included, mean GA 38.7 weeks. CRP for untreated NB varied between 10 and 16mg/L. Those that underwent antibiotic therapy had CRP values between 10 and 151mg/L. CRP for NB with POI varied between 22 and 151mg/L, treated but with no late presumption of infection between 10 and 48mg/L.A cut-off level of 20mg/l would have selected 16 without POI and missed none.
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