Thermal injuries are wide spread among home pets and are represented as a recent problem of veterinary medicine because of the lack of anti-burn drugs adapted for use in veterinary medicine. In this regard, the aim of our work is to certify the vulnerary spray “Acerbin” for medical purposes in the treatment of thermal injuries of animals and to evaluate its therapeutic potency according to the dynamics of healing burn injuries and recovery of the blood cell composition. The research was carried out on 60 laboratory white mice. Thermal injuries of the skin integument on the dorsal surface of the croup were simulated; the “Acerbin” spray was further applied. To achieve the aim, the blood samples and planimetric measured tests of the area of burn defects were taken on the 3rd, 5th, 7th, 10th and 14th day of treatment. The samples were analyzed by the quantitative content of erythrocytes, thrombocytes, leucocytes and cHb (blood hemoglobin concentration) using an automatic hematological analyzer “Abacus vet 10”. Planimetric indicators of the area of burns were subjected to mathematical processing with the calculation of the rate of epithelization of the burn injury. The obtained hematological and planimetric digital indicators were processed by statistical methods of analysis, compared and then interpreted.

The purpose of the work was to test and compare the therapeutic efficacy of the wound healing spray "Acerbin" for medical purposes and Vishnevsky's balsamic liniment in the treatment of thermal burns. The work was carried out on laboratory white mice in the amount of 60 individuals, in which thermal burns of the skin on the dorsal surface of the croup were modeled, and then the tested drugs were applied to the burn site in two experimental groups. Evaluation of therapeutic efficacy in terms of the dynamics of reduction in the area of burn injury, the index of its epithelialization and in terms of normalization of the cytomorphological composition of whole blood. The conducted studies made it possible to establish that the applications of the drug "Acerbin" contributed to a more intensive dynamics of healing of burn defects than the use of Vishnevsky's balsamic liniment, namely, on the 3rd day, the area of burns was less by 0,32%, on the 5th day - by 25,21%, on the 7th day - by 14,57%, on the 10th day - by 18,92%, on the 14th day - by 19.5%. The index of epithelialization of burns under the influence of applications of the drug "Acerbin" was higher than with applications of Vishnevsky liniment on the 5th day by 0,14%, on the 7th day - by 0,10%, on the 10th day - by 0, 10%, on the 14th day - by 0,10%. In the cytomorphological composition of the blood, applications of the drug "Acerbin" caused a more intense increase in the number of platelets than similar manipulations of Vishnevsky's liniment, namely, on the 3rd day, there were more platelets by 2,84%, on the 5th day - by 6,40%, on the 7th day. on the first day - by 5,62%, on the 10th day - by 8,16%, on the 14th day - by 14,29%, respectively. Applications of the drug "Acerbin" more effectively stopped post-burn leukocytosis than Vishnevsky's balm, that is, on the 3rd day there were less leukocytes by 35,60%, on the 5th day - by 41,34%, on the 7th day - by 24,61%, on the 10th day - by 16,73%, on the 14th day - by 11,39%, respectively. Thus, the data obtained on the therapeutic efficacy of the wound healing spray "Acerbin" in the treatment of thermal burns in animals allow us to recommend it for use in practical veterinary medicine for the treatment of combustial pathology.