Chickenpox is an urgent problem, as it is widely spread with a high level of morbidity and an increasing share in the structure of the General infectious pathology with significant economic damage. The aim of the study is to study the epidemiological and clinical features of chickenpox in adults hospitalized in Krai government-owned publicy funded health care institution «City clinical hospital No. 5, Barnaul» for the period 2008‑2018. Content analysis included statistical reporting forms No. 2 of Federal state statistical supervision «Data on infectious and parasitic diseases» in the city of Barnaul during the period 2008‑2018 of medical archival documents adult infectious Department Krai government-owned publicy funded health care institution «City clinical hospital №5, Barnaul» for the same period. Data processing was performed using calculation of intensive and extensive indicators, calculation of the arithmetic mean (X) and standard error of the average (m). Calculations were made using the STATISTICA-10 program. Consistently high rates were recorded, with an average of 64.32 ± 3.46 per 100,000 population. The percentage of hospitalized adults averaged 18.5% during the study period. Adults aged 18‑30 were more likely to be admitted to the hospital (90.3%); 41.6% were students. Adults with moderate severity were hospitalized more often (70.6%); 7 patients (1.3%) had complications: aphthous stomatitis (3 cases), pustulosis (2 cases), and pneumonia (2 cases). Patients with severe severity of the disease accounted for 2.4%, the premorbid background was burdened in 48% (HIV infection, tuberculosis). In 35% of patients with severe severity, the final diagnosis of Herpes zoster was made, all patients older than 40 years, stayed in the hospital for 20‑25 days.

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Aim. To identify the difference in the detection of yeasts of the genus Candida and their species composition in people with gastrointestinal pathology and in healthy people undergoing a regular medical checkup.Materials and methods. Clinical trial material comprised biological material from patients undergoing regular medical checkup (control group) and patients with intestinal pathology. Following the detection of fungal colonies on Sabouraud medium, identification was carried out using chromogenic agar. A number of strains were identified via mass spectrometry.Results. The study results show that the frequency of occurrence of the genus Candida is more than three times higher in patients with intestinal pathology. In addition, the study groups revealed the differences in the species composition. Candida krusei is more than 5 times more common in cases of gastrointestinal pathology.Conclusion. Due to the differences in the frequency and species composition of yeasts of the genus Candida isolated from the intestine, specialists should diagnose intestinal diseases and choose antimycotic therapy in a meticulous way.

Chickenpox is an urgent problem for public health due to its high contagiousness, wide prevalence, high incidence rates, a significant probability of medium and severe clinical course of the disease, leading to death and disability, diseases of pregnant women and the development of congenital forms of infection, as well as the carrier of the Varicella zoster virus, which leads to a chronic form of infection — shingles. Purpose: of this study was to assess epidemiological situation of chickenpox incidence among the population of the Altai region and city of Barnaul in 2001–2019 years. Materials and methods. The materials of the study were the data of statistical reporting forms № 2 of the Federal state statistical observation «Information on infectious and parasitic diseases» in the Altai region and the city of Barnaul for 2001–2019. Data processing was carried out using the calculation of intensive and extensive indicators, the calculation of the arithmetic mean (X) and the standard error of the mean (m). Statistical analysis was carried out using Microsoft Excel. Results. During the study period, there was a tendency to increase the incidence of chickenpox among the population of the Altai region and the city of Barnaul. Winter-spring seasonality was observed. Among the sick in the Altai region and in the city of Barnaul dominated children under 17 years. Summary. In order to prevent drifts and the spread of chickenpox, it is necessary to introduce vaccination against this infection into the national calendar of preventive vaccinations of the Russian Federation.