No abstract

The article presents clinical, laboratory, instrumental data in children with functional biliary dyskinesias. Studies were conducted for the period 2014–2018. on the clinical base of the National Center for Maternal and Child Welfare. The object of the study were 120 children from 7 to 14 years. It has been established that the formation of a symptom complex in most cases is ambiguous and develops against the background of various diseases that were previously experienced. The presence of a large variation in the duration of the disease indicates a delayed diagnosis of pathology. Determining the type of biliary dyskinesia allows you to choose the most effective treatment regimen.

The study was conducted on the basis of the Department of Endocrinology of the National Center for the Protection of Motherhood and Childhood. Under the supervision, there were 217 children who were divided into two groups: children with metabolic syndrome and children with normal body weight. A comparative analysis of the indicators of physical development in children with metabolic syndrome revealed that all indicators of physical data were significantly higher in the main group, which was predicted when examining children with metabolic syndrome.

The article presents a retrospective analysis of case histories of 392 children and adolescents with 1 type diabetes from 2011 to 2018. The analysis found that 60 children and adolescents suffer from diabetic nephropathy (which composes 15%). It was revealed that mostly diabetic nephropathy occurs in boys, as well as disease duration of type 1 diabetes at the time of diagnosis of diabetic nephropathy was 5–10 years.

The study presents data on the examination of 100 children aged 7 to 14 years with a disturbance of the motor-evacuation function of the bile excreting system in the hypomotor type (57 children — I clinical group) and hypermotor type (43 children — II clinical group). As a control group, 20 somatically healthy children were examined. It was shown that with hypomotor dyskinesia of the gallbladder, the activity of the cytokine (interleukin) system in the blood plasma was significantly superior to activity in hypermotor dyskinesia. Combined therapy in children’s second clinical group leads to normalization of blood levels of interleukins, whereas the children of the first clinical group stored in elevated blood concentrations of interleukin closure during treatment.