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(2 Ostryakova Ave. Vladivostok 690950 Russian Federation), 2 JSC Russian Railways hospital branch at the Vladivostok station (25 Verkhneportovaya St. Vladivostok 690063 Russian Federation) background. The study objective is to evaluate the role of endosonography and fine-needle puncture under the control of endoscopic ultrasonography (EUS) in the diagnosis and staging of pancreatic tumors. Methods. It was evaluated the results of EUS and the fine-needle puncture under the control of EUS with cytological examination on the material of 17 clinical observations. Results. In 13 patients EUS confirmed the data of magnetic resonance and computed tomography. In 7 cases it was diagnosed a highly differentiated adenocarcinoma in 3 cases-moderately differentiated adenocarcinoma, in 1 case-undifferentiated pancreatic cancer and in one case-metastasis of clear cell renal cancer. Conclusions. Endosonography is a minimally invasive, fairly safe and effective method of diagnosis of pancreas tumors, allowing in combination with fine-needle puncture and cytological study to evaluate the resectability and curable tumor as well as determine the future tactics of patients even at the stage of development of the methodology.

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