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The Future of Home Health project sought to support transformation of home health and home-based care to meet the needs of patients in the evolving U.S. health care system. Interviews with key thought leaders and stakeholders resulted in key themes about the future of home health care. By synthesizing this qualitative research, a literature review, case studies, and the themes from a 2014 Institute of Medicine and National Research Council workshop on "The Future of Home Health Care," the authors articulate a vision for home-based care and recommend a bold framework for the Medicarecertified home health agency of the future. The authors also identify challenges and recommendations for achievement of this framework.

THE response of a population of living organisms to the impact of any force of selection will vary not only with the nature of the force itself but also with the genetical architecture of the character or characters in question. The genetical architecture of a character will of course reflect those general properties which together constitute the genetic system of the population and species (Darlington, 1939, 1956) : the system of reproduction, whether asexual, subsexual, sexually inbreeding or sexually outbreeding ; and the number, organisation and relations of the chromosomes especially as reflected

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