Due to the wide spread of babesiosis in Russia, a seasonal disease caused by protozoan blood parasites from the genus Babesia, a limited number of drugs used in its treatment, this work is devoted to determining the effectiveness of 5% imidocarb solution ("Forticarb") and 12% imidocarb solution ("Pyro-stop") with babesiosis in dogs. According to the results of the study, it can be concluded that a higher therapeutic efficacy was observed when using a 5% imidocarb solution, which is due to a lower concentration of the active substance in comparison with the second group of animals. The lower concentration of the solution used was a deterrent factor in the rapid death of Babesia canis and, accordingly, in the development of side effects as a result of the formation of a huge number of toxic decay products of both the cells of one's own body and blood parasites. The use of concomitant therapy helped to minimize side effects, stimulate hematopoiesis, provided antiinflammatory, antiallergic, hepatoprotective effects.