A complex fluid containing electrolytes, metabolic substrates, enzyme cofactors, and hydrogen acceptors in concentrations similar to those of the renal cytoplasm was successfully used in preserving kidneys up to 72 h withσut artificial perfusion. The results of electron optic investigations presented in this paper demonstrate that some changes in the renal ultrastructure and enzyme reactions occur suggesting a simple low-grade hyperhydration of the renal cells and that this fluid has no irreversible, deleterious effects on these cells.
A study was carried out to investigate the biological fate of spongy polyurethane aortic prostheses after a period of implantation of 7 to 10 years in dogs. The present findings indicate that this material is in a sense accepted by the organism (not only tolerated) because almost complete reorganization of the arterial elastic structures inside the prostheses and the formation of arterial branches from the prostheses were observed.
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