e27014th International Congress on Infectious Diseases (ICID) Abstracts the end of the program, prevalence of using shared syringes among volunteers was decline to zero.Conclusion: Execution of needle and syringe exchange programs within prisons can play an important role in decreasing the number of prisoners using shared syringes and also number of shared syringes used by each prisoner. Therefore, it can greatly help medical staff with controlling blood-borne diseases.