Geoecological zoning of the eastern part of Nurinsky district of Karaganda region was performed for the first time to assess the conditions for construction of the motorway section within the framework of the One Belt, One Road idea. The paper analyzes current approaches to geoecological zoning of territorries and their use for the study area. The methodology included an integrated assessment of geo-ecological conditions with respect to geotechnical and geomorphological conditions using appropriate cartographic materials. The paper shows the role of geotechnical zoning in geo-ecological zoning of the territory. Based on the criteria selected in the ArcMap geo-information systems, maps of geo-ecological conditions and geo-ecological zoning of the eastern part of Nurinsky district, Karaganda region, were compiled. These maps can be used at pre-design stages of road or railway construction and other types of territorial development planning.