evidence presented here that the anodal component of Hp 2-1 contains only 8 and al chains makes its identity with the Hp 1-1 of the corresponding al type very likely. It would be of interest to extend these studies to the polymer bands of the rare phenotypes Hp 2-1M10 and Hp "Johnson.""1 It seems reasonable to assume that the assembly of the various chains of Hp to form the Hp 2-1 polymers occurs very soon after the chains are synthesized since artificial mixtures of Hp 2-2 and Hp 1-1, even after prolonged incubation, show no tendency to form 2-1 polymers.'2 The mechanism of this assembly is unknown. Summary.-Polymer bands of Hp 2-1, freed from the anodal component by gel filtration, are shown to contain appreciable amounts of a1 chains which are characteristic of Hp 1-1. This is taken as evidence in support of Allison's hypothesis that the polymers of Hp 2-1 differ from those of Hp 2-2 in containing Hp' gene products as an integral part of their structure. The anodal component of Hp 2-1 is shown to resemble Hp 1-1 in its chain composition. The author wishes to thank Miss Elaine Henry for technical assistance.

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