The design of environmentally friendly approach to the synthesis of biologically important compounds without compromising the yield has been the focus of many chemists in recent years. The development of one-pot synthesis of heterocycles in the presence of ionic liquids (ILs), used as both environmental media and catalysts is efficient and environmentally sustainable. This review highlights the one-pot synthesis of imidazoles in acidic ILs in the past decade. Some reviews have been done on imidazoles, such as their pharmacological importance. Hence we decided to focus on their synthesis in acidic ionic liquids, which the authors are not aware of any published literature.