In this research; the release of 5-Fluorouracil (5-FU) from different ionically crosslinked alginate (Alg) beads was investigated by using Fe³⁺, Al³⁺, Zn²⁺, and Ca²⁺, ions as crosslinking agent. The prepared beads were characterized by Fourier Transform Infrared Spectroscopy (FTIR) Differential Scanning Calorimetry (DSC) and Scanning Electron Micros-copy (SEM). The drug release studies were carried out at three pH values 1.2, 6.8 and 7.4 respectively each for two hours. The effects of the preparation conditions as crosslinker type, drug/polymer (w/w) ratio, crosslinker concentration and time of exposure to crosslinker on the release of 5-FU were investigated for 6 hours at 37℃. It was observed that 5-FU release from the beads followed the order of Fe > Zn > Al > Ca-Alg and increased with increasing drug/polymer ratio. At the end of 6 hours, the highest 5-FU release was found to be 90% (w/w) for Fe-Alg beads at the drug/polymer ratio of 1/8 (w/w), crosslinker concentration of 0.05 M, exposure time of 10 minutes respectively. The swelling measurements of the beads supported the release results. Release kinetics was described by Fickian and non-Fickian approaches

The paper analyzes the key features, performance, efficiency, and electrical characteristics of organic PV cells to highlight the latest trends and advancements by using comparative tables and a comprehensive SWOT analysis.

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In this study, polymeric beads of sodium alginate (NaAlg) and its blend with poly(vinyl alcohol) (PVA) were prepared by crosslinking with glutaraldehyde (2.5% v/v) and hydrochloric acid (3% v/v) for the release of naproxen sodium (NS). The prepared beads were characterized with Fourier transform infrared spectroscopy, and pictures of the beads were determined with an optic microscope. The release studies were carried out at three pH values (1.2, 6.8, and 7.4) for 2 h. The effects of the preparation conditions, including the PVA/NaAlg (w/w) ratio, drug/polymer (w/w) ratio, and time of exposure to the crosslinker, on the release of NS were investigated for 10 h at 37°C. The release of NS decreased with the PVA/NaAlg (w/w) ratio and drug/polymer ratio increasing. At the end of 10 h, the highest release of NS was found to be 84% for the 1/2 PVA/NaAlg (w/w) ratio. The swelling measurements of the beads supported the release results. The release kinetics were described with Fickian and non‐Fickian approaches. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009