Background: Ichthyosis linearis circumflexa is a rare form of ichthyosis characterized by polycyclic and annular lesions which are bordered by a double-edged scale. Netherton syndrome is a genodermatosis in which ichthyosis linearis circumflexa is accompanied by characteristic hair shaft abnormalities and atopic diathesis. Different treatment modalities such as emmolients, keratolytics, calcipotriene, topical corticosteroids, topical calcineurin inhibitors, systemic retinoids, phototherapy and photochemotherapy have been used with variable results. Topical therapies may result in considerable absorption because of the defective barrier function in ichthyosis linearis circumflexa/Netherton syndrome.
Main observation:A 12-year-old patient diagnosed as ichthyosis linearis circumflexa demonstrated considerable improvement with narrowband UVB phototherapy at the end of 30 sessions.
Conclusion:Short-term narrowband-UVB may an effective treatment option in patients with ichthyosis linearis circumflexa/Netherton syndrome. (J Dermatol Case Rep. 2015; 9(4): 110-112) Ichthyosis linearis circumflexa in a child. Response to narrowband UVB therapy.
ecker nevüs (BN) veya diğer adıyla pigmente kıllı epidermal nevüs, Becker melanozu ilk kez 1948 yılında Becker tarafından iki genç erkek hastada tanımlanmıştır.1 Erkeklerde kadınlara göre 6 kat daha sık görülen BN, genellikle peripubertal dönemde ortaya çıkmakta-dır. BN keskin sınırlı, unilateral, düzensiz hiperpigmente makül ve yamalarla karakterize, birlikte hipertrikozisin bulunabildiği hamartomatöz bir lezyondur ve sıklıkla sırt, omuz, göğüs ve kolların üst kısımlarında yerleşim göstermektedir.2,3 Literatürde çok az sayıda alt ekstremite yerleşimli hasta mevcuttur. 4 Yüz yerleşimli BN ise çok daha nadir saptanmaktadır.
5-10Turkiye Klinikleri
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.