The BESSt formula was statistically significantly more accurate than the other techniques tested. Thus, it could significantly improve intraocular lens power calculation accuracy after keratorefractive surgery, especially when pre-refractive surgery data are unavailable.

Seven weeks after small-incision phacoemulsification, the CCTI induced less SIA than the CCOI; however, there were no significant differences in the final UCVA and BCVA.

In eyes with preoperative astigmatism less than 2.60 D, on-axis CCI phacoemulsification induced slightly more flattening along the incision meridian than temporal CCI phacoemulsification, although the differences were not significant. The on-axis CCI was associated with significantly greater absolute torque and angle of error than the temporal CCI. These factors could limit the benefit of placing the incision on axis when the aim is to reduce preoperative astigmatism in phacoemulsification.

The presence of heterozygous loss-of-function alleles in the ZNF469 gene did not cause keratoconus in the individuals examined. None of the rare nonsynonymous ZNF469 variants identified in the familial cohort conferred a high risk of keratoconus; therefore, genetic variants contributing to disease pathogenesis in these 11 families remain to be identified.

Dr. Borasio is the creator of Astig Plot. No other author has a financial or proprietary interest in any material or method mentioned.