A continuous flow methodology is described which gives α-alkylated ketones in good yields, avoids cryogenic temperatures, excessive exposure to alkyllithiums/alkylhalides, and can be easily and continuously scaled-out (to >3 g in 45 min).
I Thh report was prepared u an rcwunt of oovernment sponmred work. Neither the United Statn, nor the Commission, nor any person acting on behalf of the Camminion: A. Makn m y warranty or representation, expreu or implied, with respect to the accuracy, complettnccs, or uwfulneu.of the information contained in t h i~ report, or that tho me of any information, apparatw, method, or procws discloled In this rdport lvl&y hbt Illlriqa pdrrtrly I owned rights; or I B. Assuma any liabilities with respect to the uw of, or for damym maultin# from the use of any information, apparatus, method, or process disclmod in this report. As used in the above, "person acting on behalf of the Commission" includn m y employee or contractor of the Commission, or employee of such contractor, to the extent that such employee or contractor of the Commission, or employee of such contractor prepares, dheminates, or providm accea to, ,any information punurnt to hh employment m eontract with the Commisdon, or his employment with such watractm.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.