Obesity, metabolic syndrome, and type-2 diabetes mellitus are 3 interrelated conditions that share a number of pathophysiological mechanisms and that are frequently observed to lead, in succession, to cardiovascular complications. The fact that their prevalence is increasing alarmingly should prompt all healthcare professionals urgently to implement measures to prevent these complications. The most effective, though also the least adopted, are those related to lifestyle modification. Drug treatment targeted at controlling risk factors (eg, hypertension, dyslipidemia, and thrombophilia), metabolic abnormalities, and excess weight is also necessary.
Obesidad, síndrome metabólico y diabetes: implicaciones cardiovasculares y actuación terapéuticaObesidad, síndrome metabólico y diabetes mellitus tipo 2 son tres enfermedades interrelacionadas que comparten mecanismos de aparición y evolución y con frecuencia se van combinando sucesivamente y ocasionan complicaciones cardiovasculares. Su prevalencia crece alarmantemente y debería impeler a los profesionales de la salud y a los gestores a implantar medidas urgentes para prevenir la aparición de complicaciones. Las más eficaces, aunque menos practicadas, son las relacionadas con el estilo de vida. También son necesarios tratamientos farmacológicos destinados al control de los factores de riesgo (hipertensión, dislipemias, trombofilia), las alteraciones metabólicas y el propio exceso de peso.Palabras clave: Diabetes. Síndrome metabólico. Obesidad.
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