The consumption of avocado is of great importance in the daily diet of the human being, since this fruit contains high levels of Omega 3 and various vitamins (B6, B9 and E) and minerals (magnesium, iron, zinc and phosphorus). Today, Mexico is one of the main avocado producers worldwide. However, the high demand and the low production of this fruit makes the price of avocado more expensive and, therefore, the Mexican population reduces its consumption and seeks nutritional alternatives. For this reason, this research aimed to propose the manufacture of solid avocado tablets (based on pharmaceutical techniques) by granulating and compacting the dehydrated powder of this fruit. This was carried out under a mixed approach by applying quantitative and qualitative technologies to systematic, critical and empirical processes in order to choose the best granulation technique, the ideal binder and the type of compaction to use to achieve solid tablets using dehydrated avocado powder. This tablet aims to preserve the same nutrients as natural avocado and reach all sectors of the population to generate a sustainable and human survival environment.

Pharmaceutical industry produces safe, effective, affordable, and quality medicines used to guarantee a healthy life and promote the well-being of the entire population in a sustainable way. Currently, the solid dosage form is the preferred formulation for human use. However, the large scale production of these medicines it requires well-tested formulation and appropriate equipment because any substantial variation in the development of the pharmaceutical product can alter the final quality of the product, causing the entire manufactured batch to be discarded. For this reason, this research aimed to analyze and understand the behavior of the variables involved in the wet granulation process while scaling from a laboratory system and a production line unit to transfer the results obtained to a large-scale production unit of solid dosage forms to meet the health needs of the world population. This study was carried out under a mixed approach applying quantitative and qualitative technologies to explain and predict the behavior of the involved variables while scaling from a laboratory system to a production line unit. It was found that there are some regularities and causal relationships between geometric, kinematic, and dynamic similarities.