gation such a study was made of normal defibrinated pig's blood under ordinary conditions, on the one hand, and after radiation with rays of various wave length on the other hand.The tests were performed by measuring the growth of liviiig seedlings of the plant Lupinus albus immersed in definite nutrient solution with and without admixture of one per cent of blood. Specimens of pig's blood were exposed to the action of ultraviolet rays for periods varying from 10 to 30 minutes, the radia-

water vehicles and has proved to be very economical, easy

No abstract

When an animal is immunized against bacterial toxins (Seng, z Joachim, a Atkinson, 4 Ledingham ~) and against foreign proteins (MolP), there result certain characteristic quantitative changes in the proteins of the blood plasma. The content of serumglobulin is strikingly increased, even up to double the normal amount; at the same time, there is a diminution in the serumalbumin. Similar changes have been said to occur during starvation ;7 however, Moll has denied that the inanition is the cause of the globulin increase observed in precipitin sera.Atkinson s showed that this serumglobulin increase is in some degree proportional to the antitoxic (diphtheria) potency of the serum. His analyses give figures for the protein precipitable on saturation with magnesium sulphate; this " globulin , , 9 paralleled more or less the gross changes in the antitoxic potency in the serum for the one horse so examined. With his other observations on the increased " globulin " and the antitoxic content of antitoxic 1Received for publication January I8, I9iO.

Since the discovery b y N e t t e r (1) and Levaditi (2) of the presence of virus-neutralizing antibodies in the blood, both from human convalescents and from monkeys recovered from experimental poliomyelitis, several attempts have been made to immunize large animals with a view to quantity production of therapeutic serum.