Endometriosis is the presence of ectopic endometrial tissue that can respond to ovarian hormonal stimulation. Although it is uncommon, extrapelvic endometriosis can form a discrete mass known as an abdominal wall endometrioma. Endometriomas are thought to be caused by transfer of endometrial cells into a surgical wound, most often after a cesarean delivery. Endometriomas are diagnosed via ultrasound, computed tomography, magnetic resonance imaging, and ultrasound-guided fine needle aspiration. Treatment options can be medical, but surgical excision is the treatment of choice. Perioperative nursing care includes patient teaching, taking steps to prevent surgical site infection and inadvertent hypothermia, ensuring availability of supplies (eg, the graft for abdominal wall repair if needed), and postoperative pain management.
Background
This individual-patient data meta-analysis investigated the effects of enhanced recovery after surgery (ERAS) protocols compared with conventional care on postoperative outcomes in patients undergoing pancreatoduodenectomy.
Methods
The Cochrane Library, MEDLINE, Embase, Scopus, and Web of Science were searched systematically for articles reporting outcomes of ERAS after pancreatoduodenectomy published up to August 2020. Comparative studies were included. Main outcomes were postoperative functional recovery elements, postoperative morbidity, duration of hospital stay, and readmission.
Results
Individual-patient data were obtained from 17 of 31 eligible studies comprising 3108 patients. Time to liquid (mean difference (MD) −3.23 (95 per cent c.i. −4.62 to −1.85) days; P < 0.001) and solid (−3.84 (−5.09 to −2.60) days; P < 0.001) intake, time to passage of first stool (MD −1.38 (−1.82 to −0.94) days; P < 0.001) and time to removal of the nasogastric tube (3.03 (−4.87 to −1.18) days; P = 0.001) were reduced with ERAS. ERAS was associated with lower overall morbidity (risk difference (RD) −0.04, 95 per cent c.i. −0.08 to −0.01; P = 0.015), less delayed gastric emptying (RD −0.11, −0.22 to −0.01; P = 0.039) and a shorter duration of hospital stay (MD −2.33 (−2.98 to −1.69) days; P < 0.001) without a higher readmission rate.
Conclusion
ERAS improved postoperative outcome after pancreatoduodenectomy. Implementation should be encouraged.
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