Ms. Gabryte and Mr. Danielius are paid employees of Light Conversion Ltd. Mr. Danielius is a shareholder of Light Conversion Ltd. No other author has a financial or proprietary interest in any material or method mentioned.
The solid-state femtosecond UV laser system seems an attractive alternative to the currently used ophthalmic argon-fluoride excimer laser system because of its small footprint, silent operation, and ability to generate femtosecond light pulses at both 1027 nm (suitable for flap creation) and 205 nm (corneal ablation).
New-generation 205-nm femtosecond laser irradiation produced a genotoxic effect by inducing strand breaks in the DNA of murine bone marrow cells in vitro. Research on the possible genotoxic effects of this laser on corneal and skin epithelial cells in vivo is needed.
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