To aid in knowledge of macrocyclic complexes and biomedical scientists, we are presenting here a review article with compilation of work done so far along in relation to macrocyclic ligands and their metal complexes. The metal ion chemistry of macrocyclic ligands has now become a major subdivision of coordination chemistry. This overview focuses on developments in design, synthesis, and self-assembly of metal-based architectures and ligands related to macrocyclic chemistry.

Monometallic Complexes of germanium(IV) with macrocyclic ligands have been synthesized and characterized by elemental analysis, molar conductance , infrared spectra, 1 H NMR and 13 C NMR spectral studies. The molar conductance of 10 −3 M solutions of these complexes at the room temperature indicates that the complexes are 1:2 electrolytes in nature. On the basis of chemical composition there presentation of the complexes as [Ge(OAML)nCl2]Cl2 (n=1-5) has been proposed. These synthesized complexes have also been tested against several species of pathogenic fungi and bacteria in order to evaluate their antimicrobial properties.

Review: 139 refs.