Adel.M. Shaiabyefa/. high levels in fish groups exposed to the high concentrations of the herbicide, also, glucose and total plasma lipids were increased significantly in all treated groups. Meanwhile the total plasma protein was strongly decreased and the effects were dose-dependent, as well as the fecundity, gonado-somatic index and hepato-somatic index. Estradiol and testosterone hormones showed severe changes in females and males specially those exposed to the high concentrations of butataf herbicide. Also, T3 and T4 recorded the same trend.