Introduction Preeclampsia is a pregnancy-specific syndrome. One of the hypotheses concerning the etiology of preeclampsia is vitamin D deficiency during pregnancy. Method and Materials The present study is a randomized controlled clinical trial which aims to determine the effect of vitamin D supplement on reducing the probability of recurrent preeclampsia. 72 patients were placed in control group while 70 patients were randomized to the intervention group. The intervention group received a 50000 IU pearl vitamin D3 once every two weeks. The control group was administered placebo. Vitamin D or placebo was given until the 36th week of pregnancy. Results The patients in intervention group have significantly lower (P value = 0.036) probability of preeclampsia than patients in the control group. The risk of preeclampsia for the control group was 1.94 times higher than that for the intervention group (95% CI 1.02, 3.71). Conclusion The intended intervention (i.e., prescription of vitamin D) has a protective effect against recurrent preeclampsia. Vitamin D supplementation therapy in pregnancy could help in reducing the incidence of gestational hypertension/preeclampsia. Registration This study has been registered in Iranian Registry of Clinical Trials (IRCT) site with ID number IRCT2017010131695N1.

Ab s t r a c tPurpose: Global School-based Student Health Survey (GSHS) is a project supported by the World Health Organization to assess adolescent health-risk behaviours and protective factors. The present study reports test-retest and internal consistency reliability as well as Content Validity Index (CVI) for the Persian version of GSHS and Global Youth Tobacco Survey (GYTS) adapted for Iranian students. Methods:The original English GSHS, GYTS and Optional Shisha modules were translated and back-translated, pilottested, reformed and corrected for clarity. The back-translated and English versions were compared and the Persian version was then edited to reach consistency for two versions. In order to evaluate the performance of this measure for our study sample (n= 47), we examined its test-retest reliability, internal consistency, and correlation between total test and re-test scales score as well as CVI. Results:The internal consistency (Cronbach's alpha) for the whole GSHS Core modules was 0.69, and for CoreExpanded GSHS, GYTS and Optional Modules for Shisha was 0.90. Test-retest reliability varied between 0.51 and 1.00 for Core and 0.23 to 1.00 for Core-Expanded GYTS and Optional Modules of Shisha. Total test and re-test scales score for GSHS Core varied from 0.64 to 1.00, and for Core-Expanded GSHS, GYTS and Optional Modules of Shisha varied 0.67 to 0.91. Conclusion:The Persian version of GSHS Core, Core-Expanded and GYTS has acceptable reliability and validity, and can serve as a reliable instrument for Persian-speaking communities.

Background Physical inactivity and sedentary behaviour are the main risk factors for non-communicable diseases in all stages of life. However, there is a lack of reliable data regarding the recommended level of physical activity and its correlates related to physical inactivity and sedentary behaviour among school students in Iran. The aim of the present study was to report the prevalence and correlates of physical activity/inactivity and sedentary behaviour among Iranian high school adolescents. Methods The Global School-based Student Health Survey (GSHS) was used for data collection. Related data comprising socio-demographics, health risk behaviour and protective factors were obtained from 1517 high school students. Multivariate logistic regression was used to assess the association between relevant independent variables (e.g. gender) and the dependent outcome variable (physical inactivity/sedentary behaviour). Results The prevalence of recommended physical activity by WHO was 27.8%, physical inactivity 72.2% and sedentary behaviour 71.4%. Being female, being overweight or obese, walking/cycling to or from school on 1–4 days, sitting 3 or more hours/day (sedentary behaviour), insufficient vegetable intake, being bullied and lack of parental support, peer support and parental connectivity (protective factors) were positively associated with physical inactivity. On the other hand, walking/cycling to or from school on 5–7 days and inadequate fruit intake were negatively associated with physical inactivity. Walking/cycling to or from school on 1–4 days, being physically inactive, inadequate fruit intake and being bullied were positively associated with sedentary behaviour. Conclusion The prevalence of physical inactivity and sedentary behaviour was high in our studied sample. Interventions that address the issue of active school transport, sedentary behaviour, fruit and vegetable intake, family and peer support and bullying should be given more priority by the public health authorities.

No abstract