N-acetyl derivative conjugated with glucuronic acid and sulphate. The extent of sulphate conjugation corresponds to 32 % of the dose.3. The metabolism ofm-acetotoluidide is similar to that of the ortho isomer; 25% is oxidized to the corresponding N-acetamidobenzoic acid, and the only other metabolite detected was 5-amino-o-cresol which has been isolated. This is probably excreted as its N-acetyl derivative conjugated with glucuronic acid and sulphate; 10% of the dose is excreted as an ethereal sulphate.4. p-Acetotoluidide is virtually completely oxidized to p-acetamidobenzoic acid, 10% being excreted as ester glucuronide. There is,no conjugation with sulphuric acid.5. o-and m-acetotoluidides cause an abnormally high excretion of reducing material in urine. The reason for this has not been determined.The sulphate estimations were carried out by Mr P. B. Wood, to whom the authors' thanks are due. We are also indebted to the Royal Society for a Government Grant which defrayed part of the cost of the investigation.

The fungus Polyporu8 benzoinus (Wahl.) Fr., although comparatively rare in Britain, is fairly common on the Continent, particularly in Sweden, where it attacks coniferous logs, especially Abie8 species. It produces in culture a marked aromatic odour and for this reason came under examination in our investigation of the odoriferous products formed by some of the wood-rotting fungi (Birkinshaw & Findlay, 1940; Birkinshaw, Bracken &

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