Background: Urinary tract infections (UTI) are the second most frequent infection in the geriatric population, related to an increased likelihood of hospitalization. The current study aimed to determine the spectrum of antimicrobial susceptibility for community-acquired urinary pathogens among geriatric patients. Methods: A cross-sectional study was carried at Khartoum state Hospitals, Sudan. Data were collected using questionnaires. Urine cultures and antimicrobial susceptibility were performed, serum levels of IgG were determined using an enzyme-linked immunosorbent assay (ELISA) kit. Result: The overall prevalence of UTI in geriatric was 55%. Gram-negative isolates were significantly highly frequent (67.6%), Escherichia coli was predominant pathogens (46%) followed by Enterococcus faecalis (13%), and Staphylococcus aureus (10%). High resistance to Ampicillin (80-100%) and low susceptibility to co-trimoxazol and Norfloxacin was revealed in Gram-negative isolates, whereas Gram-negative bacteria showed susceptibility to Amikacin, Gentamicin, Netilmicin, and Piperacillin from (60-100%). The result of IgG antibodies by ELISA suggests that the Esherichia coli antigen may be an antigen with wide cross-reactivity, suitable for use as an objective test to identify Enterobacteriaceae urinary infection. Conclusion: High frequency of significant bacteriuria particularly Gram-negative isolates were revealed in the geriatric population, with an increase of gram-negative isolates and bacterial antibiotic resistance was very common.