with antibiotic leftovers or by acquiring antibiotics directly in the pharmacy without a prescription), are behaviours directly related with this misuse, revealing the necessity of interventions directed to health professionals. The aim of this study is to improve the consumption of antibiotics through an educational intervention directed to community pharmacists and primary care physicians. Material and Methods: A cluster randomized trial in the region center of Portugal. Of the 8 clusters, 4 clusters received an educational intervention and the other four clusters did not received any intervention and were included in the control group. Educational intervention consisted of group sessions with physicians and group sessions with pharmacists. In the sessions groups it was presented information about the problem of microbial resistances and each sessions was focused in the identified attitudes that influence the behaviour of physician during antibiotic prescription or the behaviour of pharmacist during the dispensation of antibiotics in pharmacies. At the end of each group session, were distributed flyers and poster about the importance of the adequate use of antibiotics to be divulgated to the patients. The data of antibiotics consumption was compared between the intervention group and the control group. Results: The intervention was well received for the pharmacists and for the physicians included in the study. Comparing the consumption of antibiotics between the two groups, it was observed a decrease in the total consumption of antibiotics in the intervention group during 12 months of the follow-up period after the intervention was made. Conclusions: It was possible decrease the consumption of antibiotics through an educational intervention directed to community pharmacists and primary care physicians.

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One of every five patients being treated with medicines is also taking HM by self-medication. The health authorities and doctors should advise of the risks to health and of the counter-indications of these products.

THYMUS SERPYLLOIDES ssp. GADORENSIS is endemic in the Betic region (Spain). Gas chromatography and GC/mass spectrometry studies of its essential oil showed its major components to be carvacrol and its biosynthetic precursors (gamma-terpinene and P-cymene).

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