The analysis of information about the joint use of reliability indicators and the technical condition index in assessing the state of the main electrical equipment on the example of power distribution schemes to the power system (PDSPS) of modern thermal power plants is given. The authors proposed to enter a new parameter – the index of technical condition for failure (ITCF). Technical assessment carried out by matching the actual values of the parameters of the technical state of the functional nodes with values set normative and technical documentation, as well as manufacturers, and then determine the index of the technical condition, the technical condition index to the failure of functional units and equipment for timely planning of repairs and prevent accidents. The paper presents the results of research of algorithms which allow us to form an improved approach to planning the repair program, taking into account the peculiarities of operation of the equipment.
In the paper the essential changes in Federal Law № 219-FZ “About changes in Federal Law “On protection of the environment” and the separate acts of the law of Russian Federation” under 21.07.2014 are concerned, the mechanisms and new energy provider environment management principles are analyzed. The main field of environment protection realization from heat power facilities’ negative effects according to the new Russian environmental regulation requirements is presented. The new environmental norming and control principles for industrial facilities based on the best available technologies are determined. Their implementation issues taking into account development financing are analyzed.
Objective - to study, the dynamics of catecholamine binding on erythrocytes when modeling the stimulation and blockade of adrenergic regulation mechanisms using the cytological method
Material and methods. The number of catecholamine granules on erythrocytes was determined using silver nitrate impregnation under conditions of administration of anapriline -adrenergic receptor blocker (2 mg/kg), acute stress, activation of noradrenergic systems (maprotiline, 10 mg/kg) and a combination of these effects.
Results. The number of catecholamine granules in intact animals is 145-155 pieces/40 erythrocytes. Medium-sized granules are more common (0.6-0.9 m). After the administration of a -adrenergic receptor blocker, the total number of catecholamine granules decreases 2.8 times due to large and medium-sized granules. Under conditions of acute stress, the total number of granules increases almost 2 times due to small granules, which may be a sign of sensitization of erythrocyte membranes to catecholamines. Stimulation of the noradrenergic system causes a 20% decrease in the number of catecholamine granules due to a decrease in the number of small and medium sized granules. Under stress against the background of activation of the noradrenergic system, the number of granules on erythrocytes is reduced, which may be a sign of adrenergic receptor desensitization.
Conclusions. The number of catecholamine granules on erythrocytes decreases after the administration of a -adrenergic receptor blocker and increases during acute stress. Stimulation of the noradrenergic system is accompanied by a decrease in the binding of catecholamines, especially under conditions of acute stress, which indicates desensitization of erythrocyte adrenergic receptors. The cytological method is sensitive enough to observe the reception of catecholamines by erythrocytes when exposed to adrenergic structures.
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