The present study suggests that among healthy ambulatory subjects over 45 years living at home, sarcopenia is frequent, even to the youngest subjects of the studied population, taking place from 9 % from 45 years, until 64.3 % for the subjects over 85 years. Our findings support the hypothesis that muscle mass and function are associated with BMI and physical activity, whatever the age of the subject.

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In those cases where no mechanism comes into play to regenerate the telomeres, if telomere shortening occurs at each cell replication cycle, this indicates that the cell cannot live indefi nitely.