P ulmonary vein thrombosis has been described in several patients including those with malignancy, pulmonary veno-occlusive disease, fibrosing mediastinitis, and after lung transplantation. 1-5 Although liposarcoma frequently metastasizes to the lungs, to our knowledge pulmonary venous (tumor) thrombosis with lung infarction has not been previously mentioned as part of this disease. We report a case of liposarcoma with pulmonary metastases with secondary pulmonary venous (tumor) thrombosis and infarction, presenting 3 years after diagnosis of the original tumor.