<b><i>Purpose:</i></b> The purpose of this study was to investigate a possible relationship between systemic inflammatory markers such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), lymphocyte monocyte ratio (LMR), threatened preterm labor (TPL), and preterm premature rupture of membranes (PPROM), using complete blood cell count (CBC) parameters. <b><i>Method:</i></b> The study was carried out prospectively with patients admitted to our university hospital due to preterm labor and at risk of PPROM. The cases were divided into three groups according to their pregnancy status. Group 1 consisted of 90 patients with PPROM between 24th and 36th gestational weeks; group 2, 115 patients diagnosed with TPL between 24th and 36th gestational weeks; group 3, 101 patients over 36 weeks of gestation (control) who were not in labor. In addition to the demographic data of the patients, CBC parameters (white blood cell (WBC), Hg, Hct, Plt, lymphocyte, monocyte, mean platelet volume, PLR, LMR, and NLR) and C-reactive protein (CRP) values were examined and compared in each of the three groups. <b><i>Results:</i></b> CRP and WBC values of group 1 (PPROM) were higher than group 2 (TPL) and group 3 (control) (<i>p</i> &#x3c; 0.05 for both). Pearson correlation between the gestational age and PLR and NLR values was significant (<i>r</i> and <i>p</i> values for PLR and NLR, respectively, <i>r</i> = −0.18, <i>p</i> &#x3c; 0.001; <i>r</i> = −0.23, <i>p</i> &#x3c; 0.001). However, there was no significant difference between the groups regarding PLR, NLR, LMR, platelet, monocytes, and lymphocyte counts. <b><i>Conclusions:</i></b> Only WBC was a valuable parameter in predicting preterm labor and PPROM. Although there was no significant difference between the groups in PLR and NLR, a negative correlation was found with gestational age at delivery. CRP value is still a helpful parameter in PPROM and TPL prediction.

Total serum protein, hemoglobin and antioxidant system are essential to the body's physiological activities. Oral contraceptive pills influence the level of proteins of both types present in the blood; thus, it is found to change among pregnant women. Objectives: To scrutinize  oral contraceptive pills' effects (OCP) on total serum protein, hemoglobin and antioxidant capacity among females. Methods: The participants were divided into the experimental group (EG-60) and control group (CG,-24). 5 ml of blood was collected from each subject and marked with a different identification code. The collected blood samples were processed through laboratory protocols, and thus the targeted tests were performed to achieve the desired results. The results of tests were processed through a statistical package for social sciences (SPSS, version-26), and thus appropriate statistical tools were applied for analysis. Results: Total number of subjects in both groups were 84. Mean of CG in term of hemoglobin was 13.91 ±.92 and Mean of EG in term of hemoglobin was 14.18 ±.84. Mean of CG  in term of total serum protein was 6.75 ±.48 and  Mean of EG in term of total serum protein was 6.62 ±..31. Conclusion: Based on the analysis, the researcher concluded that contraceptive pills significantly affect total serum protein, hemoglobin and antioxidant capacity among females.

Blood urea, reactive oxygen species, and antioxidants are interconnected biochemical parameters. In case of any adverse effects of any agents, it directly affects the body's physiological activities. Objective: To examine blood urea, the state of reactive oxygen species and antioxidants associated with oral contraceptive pills (OCP) among female athletes. Methods: Participants of the study were randomly selected as participants of the study. The users of OCP were placed in the Experimental Group (EG), and the nonuser of OCP was put in (CG). Each group was comprised of twenty-five subjects. 5 ml blood was collected from all the subjects. Each subject was marked with a different identification code. The blood urea level was measured through the blood urea nitrogen (BUN) test. The balancing state of reactive oxygen species and antioxidants was measured through FRAP Assay. Results collected through both BUN and FRAP were calculated through the statistical package for social sciences (SPSS, version 26). Results: The mean and standard deviation of EG in term of blood urea was 29.23 ±7.89; df was 82, t-score was -.822, P- value was .413. A significant difference in term of FRAP between CG and EG was found, such as the mean and SD of CG were 137.95±.20.87, means and SD of EG was 110.54±.39.22, the t score was 3.23, and the P value was .002. Conclusions: Results show that OCP significantly impacts blood urea and causes an imbalance in both reactive oxygen species and antioxidants among users.

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