With the role of nurses in Health Education, there is a decrease in cases of diseases that can be avoided, in the case of sexually transmitted infections from 2016 to 2017, it was notorious that the population is becoming aware, through the lectures that are offered and given in the USF's. To analyze the incidence and prevalence of syphilis in the State of Pernambuco from 2015 to 2017. Methods Cross-sectional, quantitative, descriptive work with secondary data obtained through SES-PE, Sinan and SINASC/State Program of STIs/AIDS/HV/DGCDA/SES/PE on congenital syphilis and acquired in the years 2015 to 2017, these data provided are preliminary and gender and age group were established.