IntroductionLiposarcoma is the most commonly diagnosed soft tissue sarcoma in adults and occurs predominantly in the lower limbs and retroperitoneum. Primary mediastinal liposarcomas are rare.They are often asymptomatic and when growing to large size the presenting symptoms are related to direct invasion or compression of other thoracic organs such as the heart, great vessels and lung.Case presentationA case of a 68-year-old man with primary mediastinal liposarcoma involving the diaphragm and pericardium and successfully managed by complete surgical excision is presented. The patient's postoperative course was uneventful with no evidence of recurrence 9 months after the operation.ConclusionSurgical removal is the optimal treatment for a mediastinal liposarcoma. If the entire tumor can not be resected, surgical debulking often results in symptomatic relief. International literature has demonstrated that recurrent disease occurs and therefore a long-term careful follow up is required.
IntroductionCutaneous metastases in the facial region occur in less than 0.5% of patients with metastatic cancer. They are an important finding and are not often the first sign leading to diagnosis.Case presentationWe describe the case of a 64-year-old male patient who presented with dyspnea, pleuritic pain, loss of weight and a nodule on his left cheek. A chest X-ray revealed a left upper lobe mass with mediastinal lymphadenopathy. Excision biopsy of the facial nodule revealed small-cell lung carcinoma. Palliative chemo-radiotherapy was administered and the patient survived for 12 months.ConclusionA high index of suspicion is necessary for the early detection of facial cutaneous metastases. Appropriate treatment may prolong patient survival.
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