Hyperleukocytosis is defined as a white blood cell (WBC) count of ≥ 100,000/µL. Leukostasis refers to symptomatic hyperleukocytosis and is considered a medical emergency. In pediatric practice, hyperleukocytosis is most commonly described in leukemia and other myeloproliferative disorder, but other etiologies, such as infection, are less commonly mentioned.In this case report, a one-day-old, preterm, male baby (26 weeks of gestation) was referred for preterm care. A sepsis-induced leukemoid reaction hyperleukocytosis diagnosis was presumed, and he was successfully treated with an empirical antibiotic with a gradual improvement in WBC counts.

Juvenile fibromyalgia (JFM) syndrome is a condition under the spectrum of chronic pain syndrome. It is characterized by chronic musculoskeletal pain with multiple tender points and other associated symptoms. Diagnosis requires ruling out organic causes in addition to at least five out of 18 tender points and fulfilling three out of 10 criteria. JFM can be debilitating and overwhelming to both the patient and the physician. Management requires an incredibly careful multidisciplinary approach, including psychotherapy and physiotherapy among others.

Amyloidosis is a rare multisystem disease due to deposition of abnormal protein fragments, and cardiac amyloidosis is progressive and difficult to diagnose due to its subtle and non-specific symptoms unless the physician maintains a high degree of suspicion. This case report focuses on amyloid deposition in the heart of an 84-year-old woman who presented with symptoms of uncompensated heart failure.