Background: Sewage treatment plants are associated with various health hazards. Aim: this study aimed to assess health awareness regarding occupational hazards among workers in sewage treatment plant. Research design: descriptive research design was used. Setting: the study was conducted at the Belqas Sewage Treatment Plant in Shoubra District. Sampling: a convenience sample was used and 100 workers were included in the study. Tools of data collection: two tools were used, first tool: a structured interviewing questionnaire about socio-demographic characteristic, previous medical and surgical history, health status of workers and knowledge of workers about work environment, occupational hazards, methods of prevention and first aid. Second tool: performance sheet about safety measures and first aid. Result: revealed that 89% of workers had total poor level of knowledge, 3% of them had good level of knowledge and 8%of them had average level of knowledge . Also,90% of workers had total unsatisfactory performance. Conclusion: there was a strong statistically significant relation between the total knowledge score and the total performance score (P<0.005**). Recommendations: regular implementation of health education &training programs for workers about environmental safety, health hazards and problems related to sewage treatment plant and first aid. Proper use and maintenance of personal protective equipment.