Mulberry (Morus spp., Moracecae) is a notable medicinal and multi-functional plant. Distinct mulberry types are spread in subtropical, temperate and tropical areas all over the world. Mulberry leaves carry a number of bioactive compounds with it along with various pharmacological effects. It is a magnificent origin of nutrients, phytochemical and is been proven as nutraceutical. Mulberry leaves have a wide range of pharmacological effects having bacteriostatic, anti-hyperlipidemia, lowering blood glucose, anti-hypertensive, and antiviral properties. Mulberry leaves caloric content was determined as of carbohydrate (CHO), protein, fat, fiber, moisture and ash.  Mulberry leaves contained the uppermost amount of carbohydrate (28.37%) in T1 and the lowermost amount of moisture (5.2%) in T1. The mineral content of macro-elements and micro-elements were determined from chromium (Cr), manganese (Mn), iron (Fe), zinc (Zn), magnesium (Mg), phosphorus (P), calcium (Ca), potassium (K) and sodium (Na). The content of minerals in mulberry leaves contained the highest amount of manganese (34.7) in T1 and the lowest sodium in T1. The content of vitamins in mulberry leaves contained the fat-soluble and water-soluble vitamins β-carotene, C, B3 and B2 were determined. Amongst the vitamins, mulberry leaves contained the uppermost value of β-carotene (14.0mg) and the lowermost value of vitamin B3(0.04). Bioactive compounds of mulberry leaves were determined are rutin, catechins, alkaloids and quercetin. Among the bioactive compounds in mulberry leaves contained the uppermost value of quercetin (763mg). The total phenolic content was (0.42–0.80 mg) Conclusively, mulberry leaves is enriched with nutritional values. So, it can be used in the treatment of various disease