High NLR rates, certainly with clinical correlation, can be used as a biomarker to predict intestinal necrosis and the need for intestinal resection in patients who will undergo surgery for incarcerated hernia, particularlyin situations with lacking radiological imaging methods.

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Decreased lymphocyte count and increased neutrophil count may be associated with severe sepsis, bacteremia, and surgical stress. The neutrophil-tolymphocyte ratio (NLR) may be used to assess inflammatory conditions and surgery. We evaluated whether NLR may be useful in the differentiation between biliary and nonbiliary acute pancreatitis. Material and Methods: Data from patients aged > 18 years who were diagnosed with acute pancreatitis between January 2011 and July 2014 were evaluated retrospectively. Patients were grouped as having biliary or nonbiliary pancreatitis. The white blood cell, neutrophil, and lymphocyte counts and NLR were evaluated and compared between the 2 groups. Results: In the 225 patients with acute pancreatitis (mean age, 59±18 y; 81 male patients [36%]), most patients had biliary pancreatitis (biliary, 144 patients [64%]; nonbiliary, 81 patients [36%]). Frequency of hypertension and mean arterial pressure were lower in patients who had biliary than nonbiliary pancreatitis. The mean white blood cell, neutrophil, and platelet counts were greater in patients who had nonbiliary than biliary pancreatitis. Conclusions: Although the NLR was increased in acute pancreatitis, there were no differences in NLR between patients who had biliary or nonbiliary acute pancreatitis. Therefore, the NLR is not useful in differentiating biliary from nonbiliary acute pancreatitis. Amaç: Artmış nötrofil sayısı ile birlikte azalmış lenfosit sayısı ağır sepsis, bakteremi ve cerrahi stres ile bağlantılıdır. Beyaz kan hücrelerinin bu farklı iki kompanentinin birbirine oranıyla bulunan nötrofil-lenfosit oranı (NLR), cerrahi ve inflamasyon durumlarını değerlendirmede kullanılmaktadır. Biz bu çalışmada akut pankreatit hastalarda, biliyer ve non-biliyer pankreatitli hastaların ayrımında NLR'nin prognostik değerini araştırmayı amaçladık. Gereç veYöntem: Ocak 2011 ve Temmuz 2014 tarihleri arasında akut pankreatit tanısı almış 18 yaşından büyük hastalar geriye dönük olarak değerlendirmeye alınmıştır. Hastalar etyolojik olarak biliyerpankreatit ve nonbiliyerpankreatit olarak ikiye ayrıldı. Bulgular: Çalışmaya 255 akut pankreatitli hastanın yaş ortalaması 59±18 yıl olup, 81 tanesi (%36) erkekti. Etiyolojik faktörlere bakıldığında biliyer pankreatitli hasta sayısı 144 (%64) non-biliyer pankreatitli hasta sayısı 81 (%36) idi. Hastaların fizik muayene ve laboratuar bulguları, pankreatit etyolojisine göre karşılaştırıldığında Beyaz kan hücreleri ve nötrofil değerlerinin non-biliyer pankreatit grubunda anlamlı olarak yüksek olduğu görüldü. Sonuç: Bulgularımıza göre NLR akut pankreatitte yüksek bulunmasına rağmen non-biliyer ve biliyer pankreatit arasında NLR değerinde istatiksel olarak anlamlı bir değişme olmamıştır.

Objective: Postoperative recurrent pilonidal sinus disease is troublesome, and its treatment is a challenge. In this study, it was aimed to present the long-term efficacy of crystallized phenol treatment on postoperative recurrent pilonidal sinus disease through our results collected within the last 20 years. Material and Methods: Two hundred and twenty-seven patients who had been previously operated on and suffered from recurrent pilonidal sinus disease were enrolled. The operation was applied in our outpatient clinic under local anesthesia. Demographic data of the patients, number of crystallized phenol treatment, duration of follow-up and recurrence numbers were prospectively recorded. Treatment success and factors affecting recurrence were examined. Results: Our success rate was found as 71.5%. This success rate belongs to the group of patients who never quit treatment and complied with the treatment. The patients were followed up for a mean 45.8 months. Of the post-crystallized phenol treatment recurrences, 72.4% took place within the first five years, while 97.4% did so within the first 10 years. Mean number of crystallized phenol applications was 2.6. The longer the duration of the disease before treatment, the more recurrence was observed after treatment (p= 0.02). There was no correlation between the number of previous operations and recurrence after treatment. As the number of sinus openings increased, so did the number of applications (p= 0.001). Conclusion: Crystallized phenol treatment yields promising long-term results in recurrent pilonidal sinus disease as well and may be recommended as the first choice in recurrent pilonidal sinus disease treatment since it is an effective non-operative treatment modality.

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