In this manuscript, we report our work in the development and optimisation of a MALDI-TOF mass spectrometry assay to monitor the kinetics and inhibition of PC-PLC, a phospholipase that catalyses the hydrolysis of phosphatidylcholines.
A flexible approach to C7 keto dibenzyl butyrolactone lignans was developed and the synthesis of several natural products and their related derivatives is described herein. The developed pathway proceeds through...
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