The study was undertaken to find out the psychological effects and performance in science of MSU-University Training Centre grade 10 students after the siege happened in Marawi City. Specifically, the study sought to answer the following questions; (1) what is the psychological status of the students after the Marawi siege regarding anxiety and stress manifestation? (2) Is there a significant relationship between the psychological status and the academic performance in science of the MSU-UTC students brought about by the Marawi siege? The research study used quasi experimental with qualitative research design. A population of eighty-two (82) grade 10 students were used in the conduct of the study. The following results showed that (1) students have more worries now than before the Marawi siege ; (2) Students feel pressured because of the many requirements in school; (3) Performance of students in science and Psychological stress are not associated without psychosocial intervention or values integration; (4) While with psychosocial intervention student performance and stress are significantly related; (5) and lastly, students anxiety and performance in science both with and without psychosocial intervention are not significantly related.