Purpose: Percutaneous Nephrolithotomy (PNL), has been a breakthrough in urology practice; it can be performed in various centers, with high success rates and low morbidity and mortality rates. In this study, we aimed to investigate the effect of plasma creatinine levels upon the hemorrhage on PNL procedures. Material and Methods: Patients underwent PNL were categorized as having high plasma urea and creatinine levels. Patient age, stone size, gender, hematocrit levels and additional co-morbidities were recorded and a matching group was designed using same variables. Group 1 consisted of patients with high creatinine levels and Group 2 consisted of normal creatinine levels. Body mass index, stone size, hematocrit levels, plasma creatinine levels before and after the operation, coagulation parameter (aPTT, INR), number of access tracts, operative time, preoperative platelet number, stone free rates and transfusion rates were recorded and compared. Results: Mean plasma creatinine levels were 2,11 ± 0,44 and 0,98 ± 0,27 for Groups 1 and 2, respectively. For Groups 1 and 2, stone sizes were 29,41 ± 3,83 mm, and 29,49 ± 2,99 (p=0,317). Mean peroperative hematocrit levels were 44,88 ± 5,61 and 47,51 ± 4,61 (p=0,381) for Groups 1 and 2, respectively. Those levels were 30,27 ± 7,01 and 37,74 ± 7,11 (p=0,044) for Groups 1 and 2 post operatively. Conclusion: In conclusion, having high levels of plasma creatinine preoperatively for PNL was seen to be a risk factor for hemorrhage. If a patient has high creatinine levels preoperatively, he/she may be more prone to bleeding after PNL. Keywords: Kidney Stone, Percutaneous Nephrolitotomy, Creatinine ÖZET Amaç: Perkütan nefrolitotripsi (PNL), ürolojinin son yıllarına damga vurmuş, pek çok merkezde uygulanabilen, morbiditesi ve mortalitesi son derece düşük bir tedavi yöntemi olarak karşımıza çıkmaktadır. Biz bu çalışmamızda, PNL öncesi serum kreatinin değerindeki yüksekliğin post operatif kanama durumuna etkisini araştırmayı amaçladık. Materyal ve Metod: Kliniğimizde PNL uygulanmış olan hastalar arasında üre ve kreatinin değerleri yüksek olan hastalar ayrıldı. Bu hastaların yaşları, taş boyutları, cinsiyetleri, tedavi öncesi hematokrit değerleri ve ek ko-morbiditeleri kaydedilerek hastaların bu değerlerine benzer değerleri olan hastalar ile diğer grup oluşturuldu. Serum kreatinin Araştırma Makalesi / Research Article 221
