The COVID-19 pandemic has taken higher education in general into unprecedented times. The rapid transition from in-person to online teaching and learning proved to be difficult for students, educators, and administrators. It could be argued that medical and nursing education had an even more difficult task of determining how to effectively teach the provision of health care—a fundamentally in-person, hands-on endeavor—online. The purpose of this paper is to explore the impact that COVID-19 had on undergraduate nursing education and identify lessons learned as a result. Nursing student perspectives from 2 Midwestern universities were compiled and analyzed to identify challenges, interventions performed, and key lessons learned.