NoteMastocytosis is a heterogeneous clinical entity which is classified into four categories: 1-indolent mastocytosis (the most common form), 2-mastocytosis with an associated hematologic disorder, 3-mast cell leukemia and 4-aggressive mastocytosis.

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The history of the development of practicable electron microscope technics for examination of the formed elements of the blood was reviewed. A method found to yield good reproductions of ultrathin sections of blood cells was presented in considerable detail. The various phases of the technic were critically evaluated. The morphologic characteristics of the various formed elements of normal peripheral blood were defined in association with sample electron micrographs. Ultramicroscopic detail of neutrophils, eosinophils, basophils, lymphocytes, monocytes, platelets and erythrocytes was discussed.

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