N-Methylmorpholine and urotropine, inexpensive mild bases, have effectively been utilized as catalysts in Baylis-Hillman reaction to result in good to excellent yields (57-99%) of the products.
Novel aprotic polar solvents are selected for use towards a facile Baylis-Hillman reaction catalyzed by the standard base (DABCO) at room temperature so that less reactive aldehydes and a broad spectrum of activated olefins (including acrylamide) could be coupled under the altered reaction conditions.
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