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SummaryThe authors have examined early records of the administration of ether anaesthesia in Manchester and the lives of several medical men involved in these events. Charles Strange, a dentist and chemist, in a letter to the Manchester Guardian published on 14 January 1847, described a self-administration of ether for dental extraction. but George Bowring. a surgeon, subsequently claimed the first anaesthetic administered by a doctor in Manchester. The merits of these claims are discussed in the light of the circumstances surrounding these events.

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