The study examines the mediating role of employee empowerment in the relationship between employee relationship management and organizational agility. The survey method was used in the study using a closed-end copy of the questionnaire to collect data from three hundred and fifty-eight (358) respondents via the Google Document platform. Structural equation modeling was used to analyze the data using the PROCESS macro program as a regression-based software package. The results show that employee relationships have a significant impact on organizational agility. It was also found that managing relationships with employees improves employee empowerment because it helps them achieve their organizational goals directly by allowing them to make decisions. Finally, there is a good link between employee empowerment and organizational agility. The results also indicate that employee empowerment has a positive and important relationship with employee relationships and organizational agility. This study establishes a strong role for employee empowerment as an intermediary between employee relationship management and organizational management. This means that all employers have the greatest competitive advantage of always empowering their staff with recognized world-class talent. The study has contributed to the body of knowledge by demonstrating the RBT's adaptability in a pandemic period to optimize employee motivation at the expense of acknowledging the instinct of organizational agility in a challenging era where change occurs without warning.