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SummaryIn this paper is reported the use of Y91 as an inert-indicator in the studies of the intestinal absorption of I131-labelled substances, emphasis being given to its clinical advantages.The Y91 is not absorbed in the gastrointestinal tract, since recovery in the faeces in 22 cases was 96 ± 6.7% (S.D.) of the amount given.The Y91 and the I131-labelled substances are homogenously distributed throughout any given stool sample but their rate of excretion is not always parallel.A close correlation was found between the amount of I131 excreted as obtained from the complete faecal collection method and that of Y91-indicator method in a group of 20 subjects under special supervision.The value of the Y91 inert-indicator method where the completeness of the stool collection is doubtful is shown in 23 cases.

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