Results showed that the scale has basic psychometric requirements provided that the scale will be supported by validity studies.

Neurosis-personality disorders and eatingdisorders; old age psychiatry GlobalAssessmentof Functioning scale.d) CAGE(Ewing. 1984). e) the alcohol modulefrom a 1981version of SCAN.all with estimated reliability. Results: 160 patients with variety of diagnoses (without schizophrenia and organic conditions) were assessed: 61 with BPD. 39 with other PDs. and 60 withoutPDs. 6-monthprevalence of BPD in a Sofia psychiatric sample is 3.19% for the Clinic. 1.43% for the outpatient service, and 5.17% for the day hospital. The symptoms with highest discriminative value for BPD (i.e. descriptive validity). and the factor structureof the "borderline" syndrome(thus givingevidencefor its constructvalidity) were estimated. Acute psychoses and dysthymia are significantly more frequent in patients with BPD.The absence of any PD predicts moderately higher probability for major depression, and BPD and female sex have positive predict ive power for dysthymia. Conclusions: While evidencefor the syndromevalidity of BPD is good. it is a rarer condition. although not uncommon, in a nonWestem psychiatric sample. where constructs like "cultural anhedonia" may be relevant. Although there is modest predictive powerof axis II diagnoses for some axis I disorders,the diagnoses of "personality"and "illness" are relatively independent.

In order to determine the relevant psychosocial factors associated with onset and severity of childhood asthma, fifty children with this disease and the accompanying family member were interviewed by a psychiatrist and sociodemographic data, child's psychomotor development, psychic complaints and variables about sickness and treatment were assessed. The accompanying family member was given Zung Depression and Spielberger Anxiety Scale. 54% of the acwrnpanying persons, frequently the mother, was significantly depressed. 38% of them and 56% of them had higher than average state and trait anxiety scores respectively. The higher educated the mother is the more likely for the child to present behavioral disturbance and poor treatment compliance. In the families who are informed about the disease the compliance and acceptance of treatment is better. The reverse was true whenever the emotional factors are related with asthma attacks. Emotional factors were relevant with the asthma attack in 38% of the cases. we r e p o r t on o u r e x p e r i e n c e i n 8 p a t i e n t s w i t h d i f f e r e n t forms of c h r o n i c i n t e r s t i t i a l l u n g d i s e a s e . These i n c l u d e d l y m p h o c y t i c i n t e r s t i t i a l p n e u m o n i t i s a n d c h r o n i c b r o n c h i o l i t i s . C l i n i c a l p r e s e n t a t i o n c o n s i s t e d i n t a c h y p n o e a , c y a n o s i s . cough, c r e p i t a n t r a l e s a n d f a i l u r e t o t h r i v e . I D i a g n o s t i c work u p i n c l u d e d l u n g f u n c t i o n s t u d i e s i n a l l p a t i e n t s , bronchoscopy w i t h b r o n c h o a l v e o l a r l a v a g e [BALII i n 7 p a t i e n t s (60140) in an open circuit N2 washout technique. N2 was continuously measured with a N2-UV-analyzer and FRC calculated with a standard lung function c a r t (Sensonnedics 2600). Using a calibrated syringe (20-80 ml) as a model lung of spontaneous breathing and a rubber lung (48 ml) as a model of the ventilated lung different volumes were washed out, the i n i t i a l Fi02 i n the "lung" varying between .21 and .75 .a n d open l u n g b i o p s y i n 4 p a t i e n t s . T h e r a p y i n c l u d e d o r a l a n d i n h a l e d s t e r o i d s , i n h a l a t i o n 1 w i t h b r o n c h o d i l a t o r s and o r a l h y d r o x y c h l o r o q u i n e . While most of t h e p a t i e n t s d i d n o t r e s p o n d t o s t e r o i d s a l o n e , h y d r o x y c h l o r o q u i n e i m p r o v e d t h e c l i n i c a l and1 l a b o r a t o r y f i n d i n g s i n a m a j o r i t y of o u r p a t i e n t s . C o n c 1 u s i o n : F u r t h e r c o n t r o l l e d s t u d i e s a r e r e q u i r e d f o r p r o p p e r e v a l u a t i o n of t h e e f f e c t o f h y d r o x y c h l o r o q u i n e i n t h e t r e a t m e n t o f c h r o n i c i n t e r s t i t i a l l u n g d i s e a s e i n c h i l d r e n . 281 MEASUREMENT OF FUNCTIONAL RESIDUAL CAPACITY (FRC) WI TH HELIUMIOXYGEN ALTERED ANTIOXIDANT ENZYME ACTIVITY IN LUNGS OF NEONATAL RATS WITH (H...

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